Human Leukocyte Immunoglobulin Like Receptor Subfamily A Member 3 (LILRA3) Protein
312€ (20 µg)
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name
Human Leukocyte Immunoglobulin Like Receptor Subfamily A Member 3 (LILRA3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690604
tested applications
SDS-PAGE
Description
Human Leukocyte Ig-Like Receptor A3 Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 is produced by our Mammalian expression system and the target gene encoding Thr19-Glu439 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leukocyte Ig-Like Receptor A3 |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 46.6 kDa Sequence Fragment: Met1-Glu439 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM PBS, 150 mM NaCl, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | Q8N6C8 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily A member 3,HM31,HM43,ILT6,LIR4,CD85E,ILT-6,LIR-4,Immunoglobulin-like transcript 6,Leukocyte immunoglobulin-like receptor 4,Monocyte inhibitory receptor HM43/HM31 |
| Background | Protein LILRA3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
LILRA3 (Leukocyte Immunoglobulin-Like Receptor A3), also referred to as ILT6 or CD85e, is an intriguing member of the leukocyte immunoglobulin-like receptor (LILR) family, which is predominantly expressed on immune cells. LILRA3 is unique among LILR family members because it lacks a transmembrane domain, functioning as a soluble molecule. Found within the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, LILRA3 plays a significant role in modulating immune responses, particularly in inflammatory pathways. As a soluble receptor, LILRA3 is capable of binding various ligands, which include MHC class I molecules, and thus can modulate signaling pathways related to immune tolerance and immune response activation. Its specific function in the immune system remains somewhat enigmatic, as both pro-inflammatory and inhibitory effects have been suggested. However, it is recognized as a key player in regulating inflammation and immune homeostasis, with particular relevance in autoimmune diseases, infections, and certain cancers
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