Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) Protein
234€ (2 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx680567
Description
Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) Protein is a recombinant protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 1,Leukocyte immunoglobulin-like receptor 1, ILT2,LIR1,MIR7,PIRB,CD85J,ILT-2,LIR-1,MIR-7,PIR-B,Immunoglobulin-like transcript 2,Monocyte/macrophage immunoglobulin-like receptor 7 |
| Background | Protein LILRB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Leukocyte Immunoglobulin-Like Receptor B1 (LILRB1), also known as CD85j, ILT2, or LIR-1, is a member of the leukocyte immunoglobulin-like receptor (LILR) family that plays an important role in modulating immune responses. LILRB1 is classified as an inhibitory receptor due to its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which enable it to dampen immune activation and promote immune tolerance. The LILR family consists of receptors involved in either activating or inhibiting immune responses, and they are predominantly expressed on myeloid and lymphoid cells, including monocytes, macrophages, dendritic cells, and natural killer (NK) cells.LILRB1 is encoded by a gene located on chromosome 19q13.4 within a cluster of LILR family genes. Its expression pattern includes myeloid cells and subsets of lymphocytes, such as T cells and NK cells, indicating its wide-ranging roles in both innate and adaptive immunity. The receptor functions by binding to a broad spectrum of ligands, including major histocompatibility complex (MHC) class I molecules and human cytomegalovirus (HCMV) proteins. Through its inhibitory action, LILRB1 regulates immune responses, helping prevent excessive immune activity that can lead to tissue damage or autoimmune diseases.
Productos relacionados
Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) Protein
Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) is a recombinant Human protein expressed in …
Ver producto
Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) Antibody
Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1).…
Ver producto