Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit

715€ (96 tests)
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935106861
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name
Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251817
tested applications
ELISA
Description
Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leukocyte immunoglobulin-like receptor subfamily B member 1 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 31.2 pg/ml - 2000 pg/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q8NHL6 |
Alias | Leukocyte immunoglobulin-like receptor subfamily B member 1,Leukocyte immunoglobulin-like receptor 1, ILT2,LIR1,MIR7,PIRB,CD85J,ILT-2,LIR-1,MIR-7,PIR-B,Immunoglobulin-like transcript 2,Monocyte/macrophage immunoglobulin-like receptor 7 |
Background | Elisa kits for LILRB1 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Leukocyte Immunoglobulin-Like Receptor B1 (LILRB1), also known as CD85j, ILT2, or LIR-1, is a member of the leukocyte immunoglobulin-like receptor (LILR) family that plays an important role in modulating immune responses. LILRB1 is classified as an inhibitory receptor due to its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which enable it to dampen immune activation and promote immune tolerance. The LILR family consists of receptors involved in either activating or inhibiting immune responses, and they are predominantly expressed on myeloid and lymphoid cells, including monocytes, macrophages, dendritic cells, and natural killer (NK) cells.LILRB1 is encoded by a gene located on chromosome 19q13.4 within a cluster of LILR family genes. Its expression pattern includes myeloid cells and subsets of lymphocytes, such as T cells and NK cells, indicating its wide-ranging roles in both innate and adaptive immunity. The receptor functions by binding to a broad spectrum of ligands, including major histocompatibility complex (MHC) class I molecules and human cytomegalovirus (HCMV) proteins. Through its inhibitory action, LILRB1 regulates immune responses, helping prevent excessive immune activity that can lead to tissue damage or autoimmune diseases.
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