Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits LILRB1
proveedor
Abbexareference
abx251817Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leukocyte immunoglobulin-like receptor subfamily B member 1 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
Leukocyte Immunoglobulin-Like Receptor B1 (LILRB1), also known as CD85j, ILT2, or LIR-1, is a member of the leukocyte immunoglobulin-like receptor (LILR) family that plays an important role in modulating immune responses. LILRB1 is classified as an inhibitory receptor due to its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which enable it to dampen immune activation and promote immune tolerance. The LILR family consists of receptors involved in either activating or inhibiting immune responses, and they are predominantly expressed on myeloid and lymphoid cells, including monocytes, macrophages, dendritic cells, and natural killer (NK) cells.LILRB1 is encoded by a gene located on chromosome 19q13.4 within a cluster of LILR family genes. Its expression pattern includes myeloid cells and subsets of lymphocytes, such as T cells and NK cells, indicating its wide-ranging roles in both innate and adaptive immunity. The receptor functions by binding to a broad spectrum of ligands, including major histocompatibility complex (MHC) class I molecules and human cytomegalovirus (HCMV) proteins. Through its inhibitory action, LILRB1 regulates immune responses, helping prevent excessive immune activity that can lead to tissue damage or autoimmune diseases.
Características del producto
category
ELISA Kits
immunogen target
Leukocyte Immunoglobulin Like Receptor B1 (LILRB1)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Leukocyte immunoglobulin-like receptor subfamily B member 1,Leukocyte immunoglobulin-like receptor 1, ILT2,LIR1,MIR7,PIRB,CD85J,ILT-2,LIR-1,MIR-7,PIR-B,Immunoglobulin-like transcript 2,Monocyte/macrophage immunoglobulin-like receptor 7
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LILRB1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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