Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit

Este producto es parte de LILRB1 - leukocyte immunoglobulin like receptor B1
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251817
tested applications
ELISA

Description

Human Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leukocyte immunoglobulin-like receptor subfamily B member 1 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetLeukocyte Immunoglobulin Like Receptor B1 (LILRB1)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range31.2 pg/ml - 2000 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma, tissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ8NHL6
AliasLeukocyte immunoglobulin-like receptor subfamily B member 1,Leukocyte immunoglobulin-like receptor 1, ILT2,LIR1,MIR7,PIRB,CD85J,ILT-2,LIR-1,MIR-7,PIR-B,Immunoglobulin-like transcript 2,Monocyte/macrophage immunoglobulin-like receptor 7
BackgroundElisa kits for LILRB1
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Leukocyte Immunoglobulin-Like Receptor B1 (LILRB1), also known as CD85j, ILT2, or LIR-1, is a member of the leukocyte immunoglobulin-like receptor (LILR) family that plays an important role in modulating immune responses. LILRB1 is classified as an inhibitory receptor due to its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which enable it to dampen immune activation and promote immune tolerance. The LILR family consists of receptors involved in either activating or inhibiting immune responses, and they are predominantly expressed on myeloid and lymphoid cells, including monocytes, macrophages, dendritic cells, and natural killer (NK) cells.LILRB1 is encoded by a gene located on chromosome 19q13.4 within a cluster of LILR family genes. Its expression pattern includes myeloid cells and subsets of lymphocytes, such as T cells and NK cells, indicating its wide-ranging roles in both innate and adaptive immunity. The receptor functions by binding to a broad spectrum of ligands, including major histocompatibility complex (MHC) class I molecules and human cytomegalovirus (HCMV) proteins. Through its inhibitory action, LILRB1 regulates immune responses, helping prevent excessive immune activity that can lead to tissue damage or autoimmune diseases.

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