Human Leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2) ELISA Kit

Este producto es parte de LRIG - leucine rich repeats and immunoglobulin like domains
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531526
tested applications
ELISA

Description

Human Leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetLeucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDO94898
Gene ID9860
AliasLIG2,UFS2,LIG-2
BackgroundElisa kits for LRIG2
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

LRIG2 is a close homolog of LRIG1, sharing structural features such as LRR domains and Ig-like domains that facilitate extracellular protein interactions. LRIG2 is primarily expressed in neural tissues and the urogenital tract, suggesting roles in neural development, tissue repair, and cell signaling. Unlike LRIG1, LRIG2 has been identified as a positive regulator of receptor tyrosine kinases, enhancing growth factor signaling.  LRIG2 is implicated in glioblastomas and other aggressive cancers, where it promotes cell proliferation, migration, and survival. In non-cancer contexts, LRIG2 contributes to maintaining tissue integrity and regulating neural processes. Mutations in LRIG2 are associated with developmental disorders, including urofacial syndrome, which affects facial and urinary function. Its opposing regulatory roles compared to LRIG1 underline the diverse functionality of the LRIG family.

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