Human Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Protein
273€ (10 µg)
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935106861
info@markelab.com
name
Human Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690114
tested applications
SDS-PAGE
Description
Human Leucine-Rich Repeat-Containing Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Leucine-Rich Repeat Transmembrane Neuronal Protein 2 is produced by our Mammalian expression system and the target gene encoding Cys34-Arg422 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leucine-Rich Repeat-Containing |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 45.6 kDa Sequence Fragment: Cys34-Arg422 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | O43300 |
| Alias | GAC1,LRRN5,LRANK1,FIGLER7,Leucine-rich repeat neuronal protein 5,Glioma amplified on chromosome 1 protein |
| Background | Protein LRRN2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
LRRN2 is a neuronal protein that belongs to the leucine-rich repeat (LRR) superfamily, known for its involvement in protein-protein interactions that influence neural development and synaptic regulation. LRRN2 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus. The protein plays a key role in neuronal differentiation, axon guidance, and synaptic plasticity. Structurally, LRRN2 contains extracellular leucine-rich repeat domains that mediate interactions with extracellular matrix components and neural ligands, supporting its role in cell adhesion and signal transduction. Recent studies suggest a potential link between LRRN2 dysfunction and neurodevelopmental disorders, underscoring its importance in maintaining neural circuit integrity and proper brain function.
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