Human Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Protein

Este producto es parte de LRRN - leucine rich repeat neuronal
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273€ (10 µg)

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935106861
info@markelab.com
name
Human Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690114
tested applications
SDS-PAGE

Description

Human Leucine-Rich Repeat-Containing Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Leucine-Rich Repeat Transmembrane Neuronal Protein 2 is produced by our Mammalian expression system and the target gene encoding Cys34-Arg422 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Leucine-Rich Repeat-Containing
Host
Human
Origin
Human
Observed MW
Molecular Weight: 45.6 kDa
Sequence Fragment: Cys34-Arg422
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
20mM PB, 150mM NaCl, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
O43300
Alias
GAC1,LRRN5,LRANK1,FIGLER7,Leucine-rich repeat neuronal protein 5,Glioma amplified on chromosome 1 protein
Background
Protein LRRN2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

LRRN2 is a neuronal protein that belongs to the leucine-rich repeat (LRR) superfamily, known for its involvement in protein-protein interactions that influence neural development and synaptic regulation. LRRN2 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus. The protein plays a key role in neuronal differentiation, axon guidance, and synaptic plasticity. Structurally, LRRN2 contains extracellular leucine-rich repeat domains that mediate interactions with extracellular matrix components and neural ligands, supporting its role in cell adhesion and signal transduction. Recent studies suggest a potential link between LRRN2 dysfunction and neurodevelopmental disorders, underscoring its importance in maintaining neural circuit integrity and proper brain function.
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