Human Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) Protein
273€ (10 µg)
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935106861
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name
Human Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690114
tested applications
SDS-PAGE
Description
Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Cys34-Arg422 Tag: C-terminal 6 His tag |
| Origin | Human |
| Observed MW | Calculated MW: 45.6 kDa Observed MW (SDS-PAGE): 74 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | 0.2 µm filtered prior to lyophilization. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM PBS, 150 mM NaCl, pH 7.4, containing 5%-8% Trehalose, Mannitol and 0.01% Tween 80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | O43300 |
| Gene ID | 26045 |
| OMIM | 610868 |
| Alias | GAC1,LRRN5,LRANK1,FIGLER7,Leucine-rich repeat neuronal protein 5,Glioma amplified on chromosome 1 protein |
| Background | Protein LRRTM2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
LRRN2 is a neuronal protein that belongs to the leucine-rich repeat (LRR) superfamily, known for its involvement in protein-protein interactions that influence neural development and synaptic regulation. LRRN2 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus. The protein plays a key role in neuronal differentiation, axon guidance, and synaptic plasticity. Structurally, LRRN2 contains extracellular leucine-rich repeat domains that mediate interactions with extracellular matrix components and neural ligands, supporting its role in cell adhesion and signal transduction. Recent studies suggest a potential link between LRRN2 dysfunction and neurodevelopmental disorders, underscoring its importance in maintaining neural circuit integrity and proper brain function.
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