Human Leucine-Rich Repeat-Containing Protein 3B (LRRC3B) Protein
247€ (10 µg)
247€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Leucine-Rich Repeat-Containing Protein 3B (LRRC3B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690652
tested applications
SDS-PAGE
Descripción del producto
Human Leucine-Rich Repeat-Containing Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Leucine-Rich Repeat-Containing Protein 3B is produced by our Mammalian expression system and the target gene encoding Cys34-Tyr204 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | LRRC3B, LRP15,Leucine-rich repeat protein 15 |
| Availability | Shipped within 5-15 working days. |
| Background | Protein LRRC3B |
| Buffer | 20mM Tris, 150mM NaCl, pH8.0. |
| Category | Proteins and Peptides |
| Dry Ice | No |
| Expression | Recombinant |
| Form | Lyophilized |
| Host | Human |
| Immunogen Target | Leucine-Rich Repeat-Containing |
| Name | Human Leucine-Rich Repeat-Containing Protein 3B (LRRC3B) Protein |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
| Observed MW | Molecular Weight: 20 kDa Sequence Fragment: Cys34-Tyr204 Tag: C-terminal 6 His tag |
| Origin | Human |
| Price | 247 |
| Provider | Abbexa |
| Purity | > 95% (SDS-PAGE) |
| Reference | abx690652 |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Status | RUO |
| Storage | Store at < -20°C. |
| Tested Applications | SDS-PAGE |
| UniProt ID | Q96PB8 |
Descripcion del producto en español
Background en español
LRRC3B is a tumor suppressor protein expressed in various tissues where it modulates cell growth and apoptosis its expression is frequently downregulated in cancers such as gastric colorectal and breast cancer due to epigenetic silencing through promoter hypermethylation LRRC3B is believed to inhibit cancer progression by modulating Wnt/β-catenin signaling and other pathways involved in cell proliferation and survival loss of LRRC3B function contributes to tumorigenesis by disrupting cell cycle regulation and enhancing cellular migration and invasion studies indicate it may also influence the tumor microenvironment by regulating extracellular matrix remodeling and cell-cell adhesion its potential as a biomarker for early cancer detection and prognosis is being actively explored as is its reactivation through epigenetic therapies targeting promoter methylation further research is necessary to fully characterize its tumor-suppressive mechanisms and therapeutic applications in oncology
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