Human Leucine-rich repeat-containing protein 3B (LRRC3B) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Leucine-rich repeat-containing protein 3B (LRRC3B) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531394
tested applications
ELISA
Description
Human Leucine-rich repeat-containing protein 3B (LRRC3B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 3B (LRRC3B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-rich repeat-containing protein 3B (LRRC3B) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96PB8 |
| Alias | LRRC3B, LRP15,Leucine-rich repeat protein 15 |
| Background | Elisa kits for LRRC3B |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRRC3B is a tumor suppressor protein expressed in various tissues where it modulates cell growth and apoptosis its expression is frequently downregulated in cancers such as gastric colorectal and breast cancer due to epigenetic silencing through promoter hypermethylation LRRC3B is believed to inhibit cancer progression by modulating Wnt/β-catenin signaling and other pathways involved in cell proliferation and survival loss of LRRC3B function contributes to tumorigenesis by disrupting cell cycle regulation and enhancing cellular migration and invasion studies indicate it may also influence the tumor microenvironment by regulating extracellular matrix remodeling and cell-cell adhesion its potential as a biomarker for early cancer detection and prognosis is being actively explored as is its reactivation through epigenetic therapies targeting promoter methylation further research is necessary to fully characterize its tumor-suppressive mechanisms and therapeutic applications in oncology
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