Human Large Proline-Rich Protein BAG6 (BAG6) Protein
455€ (50 µg)
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935106861
info@markelab.com
name
Human Large Proline-Rich Protein BAG6 (BAG6) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652312
tested applications
WB, SDS-PAGE
Description
Human HLA-B Associated Transcript 3 (BAT3) Protein is a Recombinant Eukaryotic Human protein expressed in 293F cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Large Proline-Rich Protein BAG6 (BAG6) |
| Host | 293F cell |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 11.0 kDa Observed MW (SDS-PAGE): 11 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu17-Gly101 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | BAG-6,BAT3,D6S52E,G3,BCL2-associated athanogene 6,HLA-B-associated transcript 3,BAG family molecular chaperone regulator 6 |
| Background | Protein BAG6 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
BAG cochaperone 6 (BAG6) is a protein that interacts with the HSP70 chaperone to regulate the turnover and degradation of misfolded proteins, playing a critical role in the cellular response to stress BAG6 is involved in maintaining cellular protein homeostasis, particularly in the degradation of unstable proteins through the ubiquitin-proteasome pathway It helps in protein quality control by preventing the accumulation of damaged or misfolded proteins, which can otherwise lead to cellular dysfunction BAG6 also regulates autophagy, a process through which cells degrade and recycle damaged proteins and organelles under stress conditions In cancer, BAG6 has been implicated in modulating apoptosis and promoting tumor cell survival by stabilizing key signaling proteins Dysregulation of BAG6 expression is linked to neurodegenerative diseases and heart disease, where defective protein turnover contributes to tissue damage and dysfunction BAG6’s involvement in stress responses, autophagy, and protein degradation highlights its importance in maintaining cellular health and stability
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