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Human Large Proline-Rich Protein BAG6 (BAG6) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits BAG6
proveedor
Abbexareference
abx555963Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Large Proline-Rich Protein BAG6 (BAG6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Large proline-rich protein BAG6 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
BAG cochaperone 6 (BAG6) is a protein that interacts with the HSP70 chaperone to regulate the turnover and degradation of misfolded proteins, playing a critical role in the cellular response to stress BAG6 is involved in maintaining cellular protein homeostasis, particularly in the degradation of unstable proteins through the ubiquitin-proteasome pathway It helps in protein quality control by preventing the accumulation of damaged or misfolded proteins, which can otherwise lead to cellular dysfunction BAG6 also regulates autophagy, a process through which cells degrade and recycle damaged proteins and organelles under stress conditions In cancer, BAG6 has been implicated in modulating apoptosis and promoting tumor cell survival by stabilizing key signaling proteins Dysregulation of BAG6 expression is linked to neurodegenerative diseases and heart disease, where defective protein turnover contributes to tissue damage and dysfunction BAG6’s involvement in stress responses, autophagy, and protein degradation highlights its importance in maintaining cellular health and stability
Características del producto
category
ELISA Kits
immunogen target
Large Proline-Rich Protein BAG6 (BAG6)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.15 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
BAG-6,BAT3,D6S52E,G3,BCL2-associated athanogene 6,HLA-B-associated transcript 3,BAG family molecular chaperone regulator 6
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
BAG6
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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