Human LAMP1 (lysosomal-associated membrane protein 1) ELISA Kit
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Name
Human LAMP1 (lysosomal-associated membrane protein 1) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH9718
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P11279 |
| Alias | LAMPA,CD107a,LGP120,CD107 antigen-like family member A |
| Background | Elisa kits for LAMP1 |
| Status | RUO |
Background
Lysosome-associated membrane glycoprotein 1 (LAMP1) is a transmembrane protein located on the lysosomal membrane that plays a key role in lysosome integrity, autophagy, and cellular homeostasis LAMP1 is highly expressed in cells undergoing autophagy, where it contributes to lysosomal stability and fusion with autophagosomes for the degradation of cellular waste It is involved in lysosome exocytosis, which regulates plasma membrane repair, pathogen clearance, and cellular stress responses LAMP1 also serves as a marker for lysosomal activity and has been implicated in immune responses, particularly in natural killer (NK) cell-mediated cytotoxicity Dysregulation of LAMP1 expression has been observed in neurodegenerative diseases such as Parkinson’s and Alzheimer’s, where impaired lysosomal function leads to protein aggregation and cellular toxicity Additionally, LAMP1 overexpression is associated with cancer progression and metastasis, where it facilitates cellular invasion through lysosome-mediated extracellular matrix degradation Its role in maintaining lysosomal function underscores its importance in cellular health and disease pathology
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