Human KN Motif And Ankyrin Repeat Domain Containing Protein 2 (KANK2) ELISA Kit

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Description
Human KN Motif And Ankyrin Repeat Domain Containing Protein 2 (KANK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human KANK2 concentrations in tissue homogenates, cell lysates and other biological fluids.
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Product specifications
Category | ELISA Kits |
Immunogen Target | KN Motif And Ankyrin Repeat Domain Containing Protein 2 (KANK2) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.313 ng/ml - 20 ng/ml |
Sensitivity | < 0.188 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q63ZY3 |
Gene ID | 25959 |
OMIM | 614610 |
Background | Elisa kits for KANK2 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
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Human KANK2 (KN motif and ankyrin repeat domain-containing protein 2) ELISA Kit
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Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity).
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