Human Junctional Adhesion Molecule 3 (JAM3) CLIA Kit

Este producto es parte de JAM - junctional adhesion molecule
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845€ (96 tests)

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935106861
info@markelab.com
name
Human Junctional Adhesion Molecule 3 (JAM3) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495949
tested applications
CLIA

Description

Human Junctional Adhesion Molecule 3 (JAM3) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Junctional Adhesion Molecule 3 (JAM3)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
15.62 pg/ml - 1000 pg/ml
Sensitivity
< 6.5 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
JAMC,JAM-2,JAM-3,JAM-C,Junctional adhesion molecule C
Background
CLIA Kits JAM3
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

JAM3 is predominantly expressed in endothelial cells, platelets, and certain subsets of immune cells. Like JAM2, it features two extracellular Ig-like domains, a single transmembrane domain, and a cytoplasmic tail that interacts with scaffolding proteins to organize tight junctions. JAM3 plays a critical role in endothelial cell adhesion and platelet aggregation, as well as in the regulation of vascular permeability and angiogenesis. It interacts with other adhesion molecules, such as JAM2 and integrins, to mediate cell-cell interactions and leukocyte trafficking during immune responses. Additionally, JAM3 is essential for maintaining the integrity of the blood-brain barrier and regulating cell migration in response to injury or inflammation.

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