Human Interleukin 34 (IL34) Protein
559€ (50 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Interleukin 34 (IL34) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655735
tested applications
WB, SDS-PAGE
Description
Human Interleukin 34 (IL34) Protein (Active) is an Active Recombinant Human protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 34 (IL34) |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 31.2 kDa Observed MW (SDS-PAGE): 31 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | IL-34,C16orf77 |
| Background | Protein IL34 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin 34 (IL34) is a pro-inflammatory cytokine identified in 2008 through bioinformatics analysis of the human genome. Unlike most interleukins, which were discovered through their immunological properties, IL-34 was initially identified for its role as a ligand for the colony-stimulating factor-1 receptor (CSF1R), a receptor known to regulate the survival, proliferation, and differentiation of macrophages and monocytes. IL-34 functions in synergy with macrophage colony-stimulating factor (M-CSF or CSF1), which is another ligand for CSF1R, to regulate immune system homeostasis. IL-34 is secreted by several cell types, including fibroblasts, keratinocytes, neuronal cells, and epithelial cells, and is expressed across different tissues, particularly in the spleen, brain, and kidneys. The broad tissue distribution of IL-34 underscores its involvement in immune modulation in diverse physiological contexts, including neuroinflammation, autoimmune diseases, and cancer. Its role is central to macrophage biology, impacting innate immune responses, tissue repair, and inflammatory processes.
Related Products
Human IL34 (Interleukin-34) ELISA Kit
Ver Producto
Mouse IL-34 (Interleukin 34) ELISA Kit
Ver Producto