Human Interleukin 3 (IL3) Protein
253.5€ (10 µg)
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name
Human Interleukin 3 (IL3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx060183
tested applications
HPLC, SDS-PAGE
Description
Human IL-3 Protein is a recombinant protein from E. Coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 3 (IL3) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: 15 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute with sterile 18MΩ-cm H2O. |
| Tested Applications | HPLC, SDS-PAGE |
| Buffer | 10 mM phosphate buffer, 200 mM NaCl (pH 7.0). Does not contain preservatives. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at -20°C or -80°C for 2 years. After reconstituting, it can be stored at 4°C for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08700 |
| Gene ID | 3562 |
| OMIM | 147740 |
| Alias | IL-3,MCG, MULTI-CSF,Hematopoietic growth factor,Mast cell growth factor,MCGF,Multipotential colony-stimulating factor,P-cell-stimulating factor |
| Background | Protein IL3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-3 (IL3) is a cytokine, a type of signaling protein involved in regulating immune and hematopoietic (blood cell formation) responses. Cytokines are crucial to the communication between cells, particularly within the immune system, helping to modulate the body's responses to pathogens, trauma, and inflammation. IL-3 is produced primarily by activated T cells, but also by other cells including mast cells, eosinophils, and monocytes, especially in response to immune challenges. Its primary function is to regulate the growth, differentiation, and survival of pluripotent hematopoietic stem cells, as well as various lineages of blood cells, making it a key player in hematopoiesis (the formation of blood cellular components). IL-3 is important not only in normal immune responses but also in pathological conditions such as allergies, autoimmune disorders, and cancers. The signaling cascade initiated by IL-3 involves several pathways, including the JAK/STAT (Janus kinase/Signal transducers and activators of transcription) and PI3K (Phosphoinositide 3-kinase)/AKT pathways, which contribute to the proliferation and survival of various cell types
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