Human Interleukin 29 (IL29) Protein
481€ (50 µg)
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935106861
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name
Human Interleukin 29 (IL29) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655730
tested applications
WB, SDS-PAGE
Description
Human Interferon Lambda-1 (IFNL1) Protein (Active) is an Active Recombinant Human protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 29 (IL29) |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 23.7 kDa Observed MW (SDS-PAGE): 27 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly20-Thr200 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | IL29,IL-29,IFN-lambda-1,Cytokine Zcyto21 |
| Background | Protein IFNL1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interferon Lambda 1 (IFNL1), also known as IL-29, is a member of the Type III interferon family, which includes IFNL1, IFNL2 (IL-28A), and IFNL3 (IL-28B), and more recently discovered IFNL4. These cytokines are involved in antiviral immunity and have significant overlap in function with Type I interferons (such as IFN-α and IFN-β), but with distinct cellular targeting. IFNL1 plays a key role in the innate immune response, especially in protecting epithelial barriers, such as those found in the lungs, intestines, and liver, from viral infections. Unlike Type I interferons, which have broad activity across multiple cell types, Type III interferons like IFNL1 act primarily on cells that express the interferon lambda receptor (IFNLR1), which is most commonly found on epithelial cells and some immune cells like dendritic cells. This targeted action is thought to provide a more localized antiviral defense while minimizing the systemic inflammatory responses often seen with Type I interferons.
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