Human Interferon Lambda-1 (IFNL1) Protein
234€ (10 µg)
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name
Human Interferon Lambda-1 (IFNL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167129
tested applications
WB, SDS-PAGE
Description
Human Interferon Lambda-1 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interferon Lambda-1 (IFNL1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Gly20-Thr200 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 23.7 kDa Observed MW (SDS-PAGE): 27 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IU54 |
| Alias | IL29,IL-29,IFN-lambda-1,Cytokine Zcyto21 |
| Background | Protein IFNL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in ddH2O to a concentration between 0.1-0.5 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 500 µg/ml |
Descripción
Interferon Lambda 1 (IFNL1), also known as IL-29, is a member of the Type III interferon family, which includes IFNL1, IFNL2 (IL-28A), and IFNL3 (IL-28B), and more recently discovered IFNL4. These cytokines are involved in antiviral immunity and have significant overlap in function with Type I interferons (such as IFN-α and IFN-β), but with distinct cellular targeting. IFNL1 plays a key role in the innate immune response, especially in protecting epithelial barriers, such as those found in the lungs, intestines, and liver, from viral infections. Unlike Type I interferons, which have broad activity across multiple cell types, Type III interferons like IFNL1 act primarily on cells that express the interferon lambda receptor (IFNLR1), which is most commonly found on epithelial cells and some immune cells like dendritic cells. This targeted action is thought to provide a more localized antiviral defense while minimizing the systemic inflammatory responses often seen with Type I interferons.
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