Human Interleukin 27A (IL27A) Protein

Este producto es parte de IL27 - interleukin 27
Human Interleukin 27A (IL27A) Protein

Pida mas información

935106861

info@markelab.com

Precio

195€ (10 µg)

Protein IL27

proveedor

Abbexa

reference

abx654022

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Interleukin-27 Subunit Alpha (IL27) Protein is a Recombinant Human protein expressed in E. coli.


Background

Interleukin 27 (IL27) is a heterodimeric cytokine that belongs to the IL-12 cytokine family and plays a pivotal role in regulating immune responses. IL-27 is produced primarily by antigen-presenting cells (APCs), such as dendritic cells, macrophages, and monocytes, following activation by various pathogen-associated signals. Its primary function is to modulate T cell responses, particularly by promoting the differentiation of T helper 1 (Th1) cells while simultaneously limiting excessive inflammatory responses through immune suppression. This dual role positions IL-27 as a key regulator of both pro-inflammatory and anti-inflammatory immune responses. IL-27 is composed of two distinct subunits: EBI3 (Epstein-Barr virus-induced gene 3) and p28, which together form the functional cytokine. IL-27 signals through a heterodimeric receptor composed of IL-27R (WSX-1) and gp130, activating a range of signaling pathways that control immune function, including the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Interleukin 27A (IL27A)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 33.6 kDa Observed MW (SDS-PAGE): 36 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL27


dry ice

No


availability

Shipped within 5-7 working days.


alias

p28,IL30,IL-27,IL27A,IL-27A,IL27p28,IL-27 subunit alpha,IL-27-A,Interleukin-30,p28


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

Human IL-27(Interleukin-27 subunit alpha) ELISA Kit

Human IL-27(Interleukin-27 subunit alpha) ELISA Kit

proveedor

FineTest

reference

EH0193

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse IL-27(Interleukin 27) ELISA Kit

Mouse IL-27(Interleukin 27) ELISA Kit

proveedor

FineTest

reference

EM1811

reactivity

mouse

status

RUO

Precio a consultar

Ver más

Porcine IL-27A(Interleukin-27 subunit alpha) ELISA Kit

Porcine IL-27A(Interleukin-27 subunit alpha) ELISA Kit

proveedor

FineTest

reference

EP0302

reactivity

porcine

status

RUO

Precio a consultar

Ver más