Human Interleukin-23 Subunit Alpha (IL23A) Protein
234€ (2 µg)
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935106861
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name
Human Interleukin-23 Subunit Alpha (IL23A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx263461
tested applications
SDS-PAGE
Description
Interleukin-23, His Tag Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | IL23 |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q9NPF7 |
| Alias | P19,SGRF,IL-23,L-23A,IL23P19,L-23 subunit alpha,IL-23-A,Interleukin-23 subunit p19 IL-23p19 |
| Background | Protein IL23A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin 23A (IL23A), also referred to as IL-23, is a heterodimeric cytokine that plays a pivotal role in immune regulation, inflammation, and host defense. It is a member of the IL-12 cytokine family, which is integral to bridging the innate and adaptive immune systems. IL-23 is predominantly produced by antigen-presenting cells (such as dendritic cells and macrophages) and acts mainly on T cells, specifically promoting the differentiation, expansion, and maintenance of Th17 cells. IL-23 is essential for chronic inflammation and has been implicated in several autoimmune and inflammatory diseases, including psoriasis, rheumatoid arthritis (RA), Crohn’s disease, and multiple sclerosis (MS). Unlike its close relative IL-12, which promotes Th1 responses and interferon-γ (IFN-γ) production, IL-23 plays a critical role in the IL-23/Th17 axis, influencing the production of IL-17 and other pro-inflammatory cytokines that contribute to tissue inflammation
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