Human Interleukin 17B (IL17B) Protein

455€ (50 µg)
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935106861
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name
Human Interleukin 17B (IL17B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651382
tested applications
WB, SDS-PAGE
Description
Human Interleukin 17B (IL17B) Protein (Active) is an active protein from Human.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 17B (IL17B) |
| Host | E. coli |
| Assay Type | Activity: Active Sequence Fragment: Gln21-Phe180 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 22.1 kDa Observed MW: 20 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UHF5 |
| Alias | NIRF,IL-20,IL-17B,ZCYTO7,Cytokine Zcyto7,Interleukin-20,Neuronal interleukin-17-related factor |
| Background | Protein IL17B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Interleukin 17B (IL17B) is part of the broader IL-17 cytokine family, which plays a crucial role in immune responses, particularly in inflammation and host defense mechanisms. The IL-17 family is known for its involvement in mediating pro-inflammatory responses, and IL-17B is no exception, being linked to various inflammatory processes. IL-17B was discovered relatively recently compared to other interleukins, and while its functions overlap with other IL-17 family members, it has distinct roles in certain pathological conditions. IL-17B, similar to its counterparts such as IL-17A and IL-17F, is produced by different types of immune and non-immune cells. It interacts with specific receptors to modulate immune cell activities and contribute to both normal immune responses and the pathology of diseases characterized by chronic inflammation, like cancer, autoimmune diseases, and inflammatory bowel disease.
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