Human Interleukin 13 Receptor Alpha 1 (IL13Ra1) Protein

Human Interleukin 13 Receptor Alpha 1 (IL13Ra1) Protein

Pida mas información

935106861

info@markelab.com

Precio

260€ (10 µg)

Protein IL13Ra1

proveedor

Abbexa

reference

abx067444

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Interleukin 13 Receptor Alpha 1 (IL13Ra1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

Interleukin-13 receptor subunit alpha-1 (IL13RA1) is a protein that serves as a primary component of the interleukin-13 receptor (IL-13R) complex, a receptor essential for immune regulation and inflammatory responses. IL13RA1, encoded by the IL13RA1 gene, is a type I cytokine receptor that primarily binds to the cytokine interleukin-13 (IL-13), a cytokine associated with type 2 helper T cell (Th2) immune responses. IL13RA1 also participates in binding interleukin-4 (IL-4), a cytokine closely related to IL-13 in function and structure, by forming a complex with IL-4 receptor alpha (IL4RA). IL13RA1’s function in the immune system is particularly significant in responses to allergens, where it helps mediate the characteristic responses associated with allergic asthma, atopic dermatitis, and allergic rhinitis. Beyond allergy and inflammation, IL13RA1’s signaling pathways are implicated in fibrotic diseases and certain cancers, as IL-13 and IL-4 promote tissue remodeling, fibrosis, and immune modulation.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Interleukin 13 Receptor Alpha 1 (IL13Ra1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 10.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: His137-Ala210 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL13Ra1


dry ice

No


availability

Shipped within 5-12 working days.


alias

IL-13 receptor subunit alpha-1,NR4,CT19,CD213A1,IL-13Ra,IL-13R subunit alpha-1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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