Human Interleukin 12A (IL12A) Protein
234€ (2 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Interleukin 12A (IL12A) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx262144
Tested Applications
SDS-PAGE
Description
Human Interleukin-12 p35, His Tag Protein is a recombinant cytokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | IL12 p35 |
| Assay Type | Activity: Not tested Sequence Fragment: 57-253 AA. Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by proprietary chromatographic techniques, followed by sterile filtration. |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 1x PBS, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C if the entire vial will be used within 4 weeks. For long-term storage, store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29459 |
| Alias | P35,CLMF,NFSK,NKSF1,IL-12A,Cytotoxic lymphocyte maturation factor 35 kDa subunit,CLMF p35,IL-12 subunit p35,NK cell stimulatory factor chain 1 |
| Background | Protein IL12A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Concentration: 0.1 mg/ml |
Background
Interleukin 12A (IL12A) is a subunit of the heterodimeric cytokine interleukin-12, which plays a pivotal role in the immune system by bridging innate and adaptive immunity. IL12A, also known as IL-12p35, pairs with the IL12B subunit (IL-12p40) to form the active cytokine IL-12, which is essential for inducing T-helper 1 (Th1) immune responses. IL12A is produced by activated antigen-presenting cells, such as macrophages and dendritic cells, in response to infections or immune challenges. It functions by stimulating natural killer (NK) cells and CD4+ T-cells to produce interferon-gamma (IFN-γ), a cytokine critical for pathogen clearance and enhancing cytotoxic activities. Dysregulation of IL12A expression has been associated with autoimmune diseases, chronic inflammation, and cancer. Therapeutic strategies targeting IL12A, including IL-12 inhibitors or engineered cytokines, are being explored for managing these conditions and for enhancing anti-tumor immune responses.
Productos relacionados
Low Sample Volume Mouse Interleukin 12 (IL12) ELISA Kit
Mouse IL-12 ELISA kit is an ELISA kit against Mouse IL-12.…
Ver producto Low Sample Volume Human Interleukin 12 (IL12) ELISA Kit
Low Sample Volume Human Interleukin 12 (IL12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hum…
Ver producto
Human Interleukin 12A (IL12A) Protein
Human Interleukin 12A (IL12A) is a recombinant Human protein expressed in E. coli.…
Ver producto