Human Interleukin 11 (IL11) Protein

Este producto es parte de IL11 - interleukin 11
Human Interleukin 11 (IL11) Protein

Pida mas información

935106861

info@markelab.com

Precio

806€ (50 µg)

Protein IL11

proveedor

Abbexa

reference

abx651374

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Interleukin 11 (IL11) Protein (Active) is an active protein from Human.


Background

Interleukin-11 (IL11) is a member of the IL-6-type cytokine family, which plays crucial roles in regulating immune responses, inflammation, and hematopoiesis. IL-11 was first identified for its role in promoting the proliferation of hematopoietic stem cells and megakaryocytes, which are essential for platelet production. Since then, IL-11 has been implicated in various biological processes, including tissue regeneration, bone remodeling, and immune system regulation. IL-11 signals through its specific receptor complex, initiating various downstream signaling cascades, primarily through the JAK/STAT pathway. IL-11 is mainly secreted by stromal cells, fibroblasts, and epithelial cells in response to various stimuli, including inflammatory signals. While initially considered a supportive cytokine in hematopoiesis, more recent studies have shown that IL-11 plays a significant role in tissue fibrosis, chronic inflammation, and even cancer progression

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Interleukin 11 (IL11)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 25.4 kDa Observed MW: 27 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro22-Leu199 Tag: N-terminal His tag


purity

> 90%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL11


dry ice

No


availability

Shipped within 5-7 working days.


alias

AGIF,IL-11,Adipogenesis inhibitory factor,Oprelvekin


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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