Human Interleukin 11 (IL11) Protein
208€ (10 µg)
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935106861
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name
Human Interleukin 11 (IL11) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx060173
tested applications
HPLC, SDS-PAGE
Description
Human IL-11 Protein is a recombinant protein from E. Coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | IL11 |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Sequence Fragment: Full length Human IL11 Protein. |
| Expression | Recombinant |
| Purity | > 98% (HPLC) |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute with sterile 18MΩ-cm H2O. |
| Tested Applications | HPLC, SDS-PAGE |
| Buffer | 10 mM phosphate buffer, 200 mM NaCl (pH 7.0). Does not contain preservatives. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at -20°C or -80°C for 2 years. After reconstituting, it can be stored at 4°C for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20809 |
| Gene ID | 3589 |
| OMIM | 147681 |
| Alias | AGIF,IL-11,Adipogenesis inhibitory factor,Oprelvekin |
| Background | Protein IL11 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-11 (IL11) is a member of the IL-6-type cytokine family, which plays crucial roles in regulating immune responses, inflammation, and hematopoiesis. IL-11 was first identified for its role in promoting the proliferation of hematopoietic stem cells and megakaryocytes, which are essential for platelet production. Since then, IL-11 has been implicated in various biological processes, including tissue regeneration, bone remodeling, and immune system regulation. IL-11 signals through its specific receptor complex, initiating various downstream signaling cascades, primarily through the JAK/STAT pathway. IL-11 is mainly secreted by stromal cells, fibroblasts, and epithelial cells in response to various stimuli, including inflammatory signals. While initially considered a supportive cytokine in hematopoiesis, more recent studies have shown that IL-11 plays a significant role in tissue fibrosis, chronic inflammation, and even cancer progression
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