Human Interferon Alpha 1/13 (IFNA1) CLIA Kit
643.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Interferon Alpha 1/13 (IFNA1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx197177
tested applications
CLIA
Description
Human Interferon Alpha 1/13 (IFNA1) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Interferon Alpha 1/13 (IFNA1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Interferon Alpha 1/13 (IFNA1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Test Range | 7.81 pg/ml - 500 pg/ml |
| Sensitivity | 4.69 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P01562 |
| Gene ID | 3439 |
| OMIM | 147578 |
| Alias | IFL,IFN,IFNA@,IFNA13,leIF D,IFN-ALPHA,IFN-alphaD,IFN-alpha-1/13,Interferon alpha-D |
| Background | CLIA Kits IFNA1 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Interferon Alpha 1 (IFNA1) plays a critical role in the body's innate immune response to viral infections. It is a member of the type I interferon family and is produced by cells such as macrophages, dendritic cells, and lymphocytes in response to pathogenic challenges, including viral RNA or DNA. IFNA1 binds to the interferon-alpha/beta receptor (IFNAR) on target cells, triggering a signaling cascade that activates the JAK-STAT pathway. This leads to the transcription of numerous interferon-stimulated genes, enhancing antiviral defense mechanisms by inhibiting viral replication, promoting apoptosis of infected cells, and activating immune cells like NK cells and cytotoxic T lymphocytes. IFNA1 also plays a role in modulating the adaptive immune response by enhancing antigen presentation. Dysregulation of IFNA1 has been implicated in autoimmune conditions such as systemic lupus erythematosus (SLE), and recombinant forms of IFNA1 are used therapeutically for conditions like hepatitis B and C and certain cancers.
Related Products
Chicken IFN-α(Interferon α) ELISA Kit
Ver Producto
Human IFNA1(Interferon alpha-1/13) ELISA Kit
Ver Producto