Human Intercellular Adhesion Molecule 3 (ICAM3) ELISA Kit
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935106861
info@markelab.com
Precio
587.5€ (96 tests)
Elisa Kits ICAM3
proveedor
Abbexareference
abx573477Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Intercellular Adhesion Molecule 3 (ICAM3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ICAM3 concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
Intercellular Adhesion Molecule 3 (ICAM3), also known as CD50, is a member of the immunoglobulin superfamily (IgSF) that plays a crucial role in cell-cell adhesion and immune system regulation. It is expressed predominantly on leukocytes, especially resting lymphocytes, and interacts with integrins to mediate various immune responses, including leukocyte trafficking, T-cell activation, and antigen recognition. ICAM3 is particularly involved in the early stages of immune responses, functioning as a ligand for leukocyte function-associated antigen-1 (LFA-1), an integrin found on T cells and other leukocytes. ICAM-3 acts as a facilitator of immunological synapse formation, helping leukocytes adhere to antigen-presenting cells and promoting signaling pathways critical for immune activation. Its interaction with integrins also promotes adhesion between leukocytes and endothelial cells, an important step in the migration of immune cells to sites of inflammation or infection. ICAM-3 is essential in regulating leukocyte dynamics and activation during immune surveillance and host defense.
Características del producto
category
ELISA Kits
immunogen target
Intercellular Adhesion Molecule 3 (ICAM3)
reactivity
Human
test range
0.781 ng/ml - 50 ng/ml
sensitivity
< 0.4 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CD50,CDW50,ICAM-R,Intercellular adhesion molecule 3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ICAM3
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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