Human Intelectin 2 (ITLN2) CLIA Kit

Este producto es parte de ITLN - Intelectin (Omentin)
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845€ (96 tests)

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935106861
info@markelab.com
name
Human Intelectin 2 (ITLN2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495538
tested applications
CLIA

Description

Human Intelectin 2 (ITLN2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
CLIA Kits
Immunogen Target
Intelectin 2 (ITLN2)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
3.12 ng/ml - 200 ng/ml
Sensitivity
< 1.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8WWU7
Gene ID
142683
OMIM
609874
Alias
HL2,HL-2
Background
CLIA Kits ITLN2
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ITLN2 is a closely related intelectin family protein sharing structural and functional similarities with ITLN1 It is secreted and primarily expressed in the gastrointestinal tract and other epithelial tissues ITLN2 participates in innate immunity by recognizing and binding to microbial components, particularly carbohydrate moieties on pathogenic bacteria and fungi It enhances microbial clearance by facilitating phagocytosis and immune activation ITLN2 expression is regulated during infection and inflammation, playing a critical role in host defense mechanisms Unlike ITLN1, ITLN2 appears to have a more restricted expression pattern and is less associated with metabolic regulation, focusing on immune surveillance in mucosal surfaces Dysregulation of ITLN2 may impair barrier immunity and has been implicated in gut inflammation and intestinal disorders, where its deficiency could increase susceptibility to infections and inflammatory bowel diseases ITLN2 represents a valuable component of epithelial defense mechanisms against microbial challenges

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