Human Integrin Alpha-L (ITGAL) ELISA Kit
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935106861
info@markelab.com
Precio
585€ (96 tests)
Elisa kits for ITGAL
proveedor
Abbexareference
abx252696Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Integrin Alpha-L (ITGAL) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Integrin Alpha-L (ITGAL) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
Integrin subunit alpha L (ITGAL), also known as CD11a, is a protein encoded by the ITGAL gene in humans. This protein forms a part of the integrin family, which is a group of cell surface receptors that mediate various biological processes, including immune cell adhesion, migration, and signaling. ITGAL pairs with the integrin beta-2 subunit (CD18) to form the LFA-1 (lymphocyte function-associated antigen 1), a heterodimeric receptor crucial for immune responses. ITGAL’s primary role is in the immune system, where it facilitates cell-cell adhesion during the immune response, helping lymphocytes, neutrophils, and other leukocytes adhere to other cells, such as endothelial cells, antigen-presenting cells, and target cells. This integrin is particularly critical in the homing, trafficking, and activation of immune cells, including T cells, natural killer (NK) cells, and neutrophils. ITGAL mediates interactions between leukocytes and the vascular endothelium by binding to intercellular adhesion molecules (ICAMs), which are vital for immune surveillance and the body's response to infection and inflammation.
Características del producto
category
ELISA Kits
immunogen target
Integrin Alpha-L (ITGAL)
reactivity
Human
test range
0.16 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
CD11A,LFA-1,LFA1A,CD11 antigen-like family member A,Leukocyte adhesion glycoprotein LFA-1 alpha chain,LFA-1A,Leukocyte function-associated molecule 1 alpha chain
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ITGAL
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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