Human Insulin Like Growth Factor Binding Protein 7 (IGFBP7) CLIA Kit

Este producto es parte de IGFBP7 - Insulin Like Growth Factor Binding Protein 7
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845€ (96 tests)

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935106861
info@markelab.com
name
Human Insulin Like Growth Factor Binding Protein 7 (IGFBP7) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx190343
tested applications
CLIA

Description

Human Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
CLIA Kits
Immunogen Target
Insulin Like Growth Factor Binding Protein 7 (IGFBP7)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.82 ng/ml - 600 ng/ml
Sensitivity
< 0.31 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
AGM,PSF,TAF,FSTL2,IBP-7,MAC25,IGFBP-7,RAMSVPS,IGFBP-7v,IGFBPRP1,IGF-binding protein 7
Background
CLIA Kits IGFBP7
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

IGFBP7 is a member of the insulin-like growth factor binding protein family that regulates the availability and activity of insulin-like growth factors (IGFs) by binding to them with high affinity Unlike other IGFBPs, IGFBP7 also binds to insulin, modulating its signaling and promoting metabolic homeostasis IGFBP7 plays a critical role in regulating cell growth, apoptosis, and senescence and has anti-tumorigenic properties by inhibiting the mitogenic effects of IGFs Its expression is downregulated in cancers such as colorectal, breast, and prostate cancer where it acts as a tumor suppressor IGFBP7 also plays roles in cardiovascular health by influencing vascular smooth muscle cell proliferation and in fibrosis by mediating tissue remodeling and extracellular matrix deposition

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