Human Insulin-Like Growth Factor 1 Receptor (IGF1R) Protein

Este producto es parte de IGF1R - insulin like growth factor 1 receptor
Product Graph
416€ (20 µg)

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935106861
info@markelab.com
name
Human Insulin-Like Growth Factor 1 Receptor (IGF1R) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694152
tested applications
SDS-PAGE

Description

Human Insulin-Like Growth Factor 1 Receptor (IGF1R) Protein is a recombinant Human protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: Calculated MW: 102.41 kDa  Observed MW (SDS-PAGE): 110 kDa
Sequence Fragment: Met1-Asn932
Tag: C-terminal His tag
Expression
Recombinant
Purity
>95% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Lyophilized Reconstitute in sterile H2O. Do not vortex.
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.
Availability
Shipped within 5-15 working days.
Storage
Store lyophilized between -20 °C and -80 °C.
Dry Ice
No
UniProt ID
P08069
Gene ID
348
OMIM
14737
Alias
Insulin-like growth factor 1 receptor,IGFR,CD221,IGFIR,JTK13,IGF-I receptor
Background
Protein IGF1R
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

The insulin-like growth factor 1 receptor (IGF1R) is a transmembrane receptor that plays a crucial role in cellular growth, survival, and metabolism. It is activated primarily by insulin-like growth factor 1 (IGF-1), a hormone structurally similar to insulin but with distinct biological functions. IGF1R is a member of the receptor tyrosine kinase (RTK) family, which includes receptors like the insulin receptor (INSR). IGF1R signaling is essential for normal development and is involved in many physiological processes, such as cell differentiation, proliferation, and apoptosis inhibition. This receptor is also significant in pathological states, especially cancer, where it can drive tumor growth and metastasis through enhanced cell survival and proliferation pathways.
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