Human Importin Subunit Alpha-7 (KPNA6) ELISA Kit
715€ (96 tests)
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Name
Human Importin Subunit Alpha-7 (KPNA6) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx388201
Tested Applications
ELISA
Description
Human Importin Subunit Alpha-7 (KPNA6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human KPNA6 concentrations in serum, plasma and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Importin Subunit Alpha-7 (KPNA6) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O60684 |
| Gene ID | 23633 |
| OMIM | 610563 |
| Alias | KPNA6,IPOA7,Importin subunit alpha-7 |
| Background | Elisa Kits for: KPNA6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
KPNA6, also called importin-α7, is a nuclear transport adaptor protein that interacts with importin-β to mediate the nuclear import of cargo proteins containing classical nuclear localization signals (NLS). It plays key roles in cellular processes such as transcriptional regulation, cell cycle control, and DNA repair. KPNA6 is highly expressed in embryonic tissues, germ cells, and immune cells, where it supports cellular differentiation and developmental processes. It has been implicated in nuclear import during viral infections, where it facilitates the entry of viral proteins into the nucleus. Dysregulation of KPNA6 is associated with developmental defects, cancer progression, and immune dysfunction. Knockout studies reveal its critical function in early embryogenesis, nuclear transport efficiency, and maintaining proper gene expression regulation during cellular growth and differentiation.
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