Human Importin Subunit Alpha-3 (KPNA4) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for KPNA4
proveedor
Abbexareference
abx388199Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Importin Subunit Alpha-3 (KPNA4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human KPNA4 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
KPNA4, also known as importin-α3, is a nuclear transport adaptor protein that recognizes classical nuclear localization signals (NLS) in cargo proteins and facilitates their nuclear import via the importin-β pathway. KPNA4 binds cargo proteins, such as transcription factors and kinases, forming a complex that translocates through the nuclear pore complex (NPC). It is widely expressed and plays critical roles in cell cycle regulation, transcriptional control, and stress responses. KPNA4 is implicated in viral replication by mediating the nuclear import of viral proteins in pathogens like HIV and influenza virus. Dysregulation of KPNA4 has been linked to cancers, where it enhances nuclear transport of oncogenic proteins and supports tumor progression. Knockdown studies show its role in maintaining proper cellular signaling, highlighting its importance in development, differentiation, and immune responses.
Características del producto
category
ELISA Kits
immunogen target
Importin Subunit Alpha-3 (KPNA4)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
< 18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
KPNA4,IPOA3, QIP1, SRP3, Importin subunit alpha-3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
KPNA4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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