Human Immunoglobulin Superfamily Member 3 (IGSF3) Protein
611€ (20 µg)
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935106861
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name
Human Immunoglobulin Superfamily Member 3 (IGSF3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692213
tested applications
SDS-PAGE
Description
Human IGSF3 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human IGSF3 isoform 1 (O75054-1) extracellular domain (Met 1-Ala 1124) was expressed, with a C-terminal polyhistidine tag.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | IGSF3 |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: 126.6 kDa Sequence Fragment: Met1-Ala1124 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 98% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75054-1 |
| Alias | V8,LCDD,EWI-3,Glu-Trp-Ile EWI motif-containing protein 3 |
| Background | Protein IGSF3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
IGSF3 is widely expressed in epithelial and immune cells, where it plays roles in cell adhesion and immune regulation. Structurally, it contains multiple Ig-like domains and is involved in maintaining the epithelial barrier integrity and regulating immune cell interactions. IGSF3 is implicated in inflammatory diseases, where its dysregulation can lead to immune hyperactivation or loss of barrier function. Additionally, it has been linked to cancer biology, where abnormal IGSF3 expression contributes to tumor progression, metastasis, and changes in the tumor microenvironment. IGSF3 is an emerging target for research in cancer and inflammatory disorders.
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