Human Hypoxia-Inducible Factor 1-Alpha (HIF1A) Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Hypoxia-Inducible Factor 1-Alpha (HIF1A) protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Hypoxia-Inducible Factor 1-Alpha (HIF1A) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Arg575-Asn826 Tag: N-terminal His tag |
| Origin | Human |
| Observed MW | 28.4 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q16665-1 |
| Background | Protein HIF1a |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
Recombinant rat HIF1a
Ver Producto
Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody
HIF1a Antibody is a Rabbit Monoclonal antibody against HIF1a. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Ver Producto
Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody
HIF1a antibody detects endogenous levels of HIF1a. Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, Arnt 1 (also designated HIF-1 beta), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family.
Ver Producto