Human Hyaluronan Mediated Motility Receptor (HMMR) Protein

Este producto es parte de HMMR - hyaluronan mediated motility receptor
Human Hyaluronan Mediated Motility Receptor (HMMR) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein HMMR

proveedor

Abbexa

reference

abx168819

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human HMMR Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

The hyaluronan-mediated motility receptor (HMMR), also known as RHAMM (Receptor for Hyaluronan-Mediated Motility), is a protein encoded by the HMMR gene in humans. Originally identified in studies focusing on cancer cell motility, HMMR functions as a receptor for hyaluronan (HA), a component of the extracellular matrix (ECM) involved in tissue hydration, structural integrity, and cellular communication. HMMR has attracted significant scientific interest due to its roles in cellular adhesion, proliferation, migration, and wound healing. Its expression is often upregulated in cancer cells, contributing to increased cell motility and invasiveness, making it a focal point in oncology research. HMMR functions not only as a surface receptor but also intracellularly, interacting with various signaling pathways and microtubule networks, which influences cell division and chromosomal stability. Given its involvement in pathways like RAS and ERK and its interaction with the mitotic spindle, HMMR is critical in cell cycle regulation and tissue morphogenesis. Dysregulated HMMR expression has been associated with cancer progression, inflammatory diseases, and even osteoarthritis, placing it at the intersection of various physiological and pathological processes.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Hyaluronan Mediated Motility Receptor (HMMR)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 21.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn577-Lys724 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

HMMR


dry ice

No


availability

Shipped within 5-7 working days.


alias

CD168,IHABP,RHAMM,Intracellular hyaluronic acid-binding protein,Receptor for hyaluronan-mediated motility


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

Human HMMR(Hyaluronan mediated motility receptor) ELISA Kit

Human HMMR(Hyaluronan mediated motility receptor) ELISA Kit

proveedor

FineTest

reference

EH2481

reactivity

human

status

RUO

Precio a consultar

Ver más

anti- HMMR-Specific antibody

anti- HMMR-Specific antibody

proveedor

FineTest

reference

FNab03936

Tested Applications

ELISA, WB, IHC, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Precio a consultar

Ver más

Recombinant Human CD168

Recombinant Human CD168

proveedor

FineTest

reference

P4237

Tested Applications

Western Blot,ELISA

status

RUO

Precio a consultar

Ver más