Loading...
Human HYAL3(Hyaluronidase-3) ELISA Kit
proveedor
FineTestreference
EH1222Tested Applications
reactivity
humanstatus
RUOclonality
Background
Hyaluronidase PH-20 is an enzyme encoded by the SPAM1 gene in humans. It is a member of the hyaluronidase family , which have the capacity degrade hyaluronic acid—a major structural proteoglycan found in extracellular matrices and basement membranes. The human genome contains six genes related to hyaluronidases, with three of them (HYAL1, HYAL2, and HYAL3) clustered on chromosome 3, and the other three (HYAL4, SPAM1, and HYALP1) clustered on chromosome 7. The extensive homology between these six hyaluronidase genes suggests an ancient gene duplication event that occurred before the emergence of modern mammals. Hyaluronidase PH-20 plays a role in various physiological processes, including sperm function and fertilization, due to its ability to modify the extracellular matrix by degrading hyaluronic acid. Aliases: HYA1; HYAL PH-20; HYAL PH20; Hyal-PH20; HYAL1; HYAL3; HYAL5; HYALP_HUMAN; Hyaluronidase PH-20; Hyaluronoglucosaminidase PH-20; MGC26532; PH-20 Hyaluronidase; PH20; PH20 Hyaluronidase; SPAG15; SPAM-1; SPAM1; Sperm adhesion molecule 1; Sperm surface protein
Background
La hialuronidasa PH-20 es una enzima codificada por el gen SPAM1 en humanos. Es miembro de la familia de las hialuronidasas, que tienen la capacidad de degradar el ácido hialurónico, un proteoglicano estructural importante que se encuentra en las matrices extracelulares y las membranas basales. El genoma humano contiene seis genes relacionados con las hialuronidasas, tres de ellos (HYAL1, HYAL2 y HYAL3) agrupados en el cromosoma 3, y los otros tres (HYAL4, SPAM1 y HYALP1) agrupados en el cromosoma 7. La extensa homología entre estos seis genes de hialuronidasa sugieren un evento de duplicación de genes antiguo que ocurrió antes de la aparición de los mamíferos modernos. La hialuronidasa PH-20 desempeña un papel en diversos procesos fisiológicos, incluida la función de los espermatozoides y la fertilización, debido a su capacidad para modificar la matriz extracelular degradando el ácido hialurónico. Alias: HYA1; HIAL PH-20; HIAL PH20; hial-PH20; HIAL1; HIAL3; HIAL5; HYALP_HUMAN; Hialuronidasa PH-20; hialuronoglucosaminidasa PH-20; MGC26532; PH-20 Hialuronidasa; PH20; PH20 Hialuronidasa; SPAG15; SPAM-1; SPAM1; Molécula de adhesión de esperma 1; Proteína de la superficie del esperma
Características del producto
category
ELISA Kits
reactivity
human
test range
0.313-20ng/ml
assay type
Sandwich ELISA, Double Antibody
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96T
alias
HYAL3|Hyaluronidase-3|Hyal-3|Hyaluronoglucosaminidase-3|Lung carcinoma protein 3|LuCa-3
storage
2-8 °C for 6 months
or code
HYAL3
uniprot id
Quizá le pueda interesar
Hyaluronidase PH-20 (SPAM1) Antibody
proveedor
Abbexareference
abx305404Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalSPAM1 Antibody is a Rabbit Polyclonal against SPAM1.
162.5€ (20 µg)
Ver másHuman Hyaluronidase PH-20 (SPAM1) ELISA Kit
proveedor
Abbexareference
abx383398Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Hyaluronidase PH-20 (SPAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SPAM1 con...
687.5€ (96 tests)
Ver másMouse Hyaluronidase 1 (HYAL1) CLIA Kit
proveedor
Abbexareference
abx492505Tested Applications
CLIAreactivity
Mousestatus
RUOMouse Hyaluronidase 1 (HYAL1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) ...
812.5€ (96 tests)
Ver más