Human Homeodomain Only Protein (HOPX) Protein
403€ (50 µg)
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935106861
info@markelab.com
name
Human Homeodomain Only Protein (HOPX) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx675032
tested applications
WB, SDS-PAGE
Description
HOP Protein is a protein produced in Human.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Homeodomain Only Protein (HOPX) |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 63 kDa Tag: His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Tested Applications | WB, SDS-PAGE |
| Buffer | 20 mM HEPES buffer pH7.2, 80 mM NaCl, 10% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at -20°C. |
| Dry Ice | No |
| UniProt ID | P31948 |
| Gene ID | 10963 |
| NCBI Accession | NP_006810.1 |
| Background | Protein HOPX |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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HOPX antibody
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
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