Human Histamine N-Methyltransferase (HNMT) Protein

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234€ (5 µg)

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935106861
info@markelab.com
name
Human Histamine N-Methyltransferase (HNMT) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073556
tested applications
SDS-PAGE

Description

Histamine N-Methyltransferase is a recombinant enzyme.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Histamine N-Methyltransferase (HNMT)
Host
E. coli
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Origin
Human
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Storage
Store at 4 °C if the entire vial will be used within 4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P50135
Background
Protein HNMT
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

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