Human Heparin Cofactor II (SERPIND1) ELISA Kit

Este producto es parte de SERPIND1 - serpin family D member 1
Human Heparin Cofactor II (SERPIND1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

611€ (96 tests)

Elisa kits for SERPIND1

proveedor

Abbexa

reference

abx570183

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Heparin Cofactor II (SERPIND1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Heparin cofactor 2 concentrations in serum, tissue homogenates, cell lysates and other biological fluids. The analyte concentration is higher in plasma than in other sample types, therefore for plasma samples, it is recommended to use the


Background

SERPIND1 encodes Heparin Cofactor II (HCII), a serine protease inhibitor (serpin) that plays a critical role in the regulation of coagulation. It shares functional similarities with antithrombin (SERPINC1), particularly in inhibiting thrombin, a key enzyme in the coagulation cascade. However, HCII exhibits a more specialized function as its activity is highly dependent on heparin-like glycosaminoglycans (GAGs), particularly dermatan sulfate, and to a lesser extent, heparin. HCII's involvement in thrombin inhibition and its activation through GAGs have made it an essential component in controlling clot formation and preventing thrombosis, particularly in vascular tissue. HCII deficiency has been linked to a predisposition for thromboembolic disorders and cardiovascular diseases.

Características del producto

category

ELISA Kits


immunogen target

Heparin Cofactor II (SERPIND1)


reactivity

Human


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

< 16 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

HC2,LS2,HCF2,HCII,HLS2,THPH10,D22S673,Heparin cofactor 2,Heparin cofactor II,Protease inhibitor leuserpin-2,Serpin D1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

SERPIND1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human SERPIND1(Serpin family D member 1) ELISA Kit

Human SERPIND1(Serpin family D member 1) ELISA Kit

proveedor

FineTest

reference

EH12199

reactivity

human

status

RUO

Precio a consultar

Ver más

anti- SERPIND1 antibody

anti- SERPIND1 antibody

proveedor

FineTest

reference

FNab07750

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-I...

Precio a consultar

Ver más

Serpin D1 (SERPIND1) Antibody

Serpin D1 (SERPIND1) Antibody

proveedor

Abbexa

reference

abx004485

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

SERPIND1 Antibody is a Rabbit Polyclonal antibody against SERPIND1. The product encoded by this gene is a serine protein...

195€ (20 µl)

Ver más