Human Heat Shock Protein 47 / HSP47 (SERPINH1) ELISA Kit
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935106861
info@markelab.com
Precio
643.5€ (96 tests)
Elisa kits for SERPINH1
proveedor
Abbexareference
abx151784Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Heat Shock Protein 47 / HSP47 (SERPINH1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Heat Shock Protein 47 / HSP47 (SERPINH1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Heat Shock Protein 47 (HSP47)
Background
SERPINH1, also known as heat shock protein 47 (HSP47), is a member of the serpin (serine protease inhibitor) superfamily, though it functions differently from classical serpins. Unlike other serpins, SERPINH1 is not a protease inhibitor but rather acts as a molecular chaperone. It plays a crucial role in collagen biosynthesis, aiding the proper folding and stabilization of collagen molecules during their formation. As a collagen-specific chaperone, it is essential in maintaining the structural integrity of connective tissues and contributes significantly to tissue development and repair. The SERPINH1 gene is located on chromosome 11 in humans. Mutations in this gene have been associated with connective tissue disorders, notably osteogenesis imperfecta (OI), a condition characterized by fragile bones.
Características del producto
category
ELISA Kits
immunogen target
Heat Shock Protein 47 / HSP47 (SERPINH1)
reactivity
Human
test range
125 pg/ml - 8000 pg/ml
sensitivity
< 43 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
CBP1,CBP2,OI10,gp46,AsTP3,HSP47,PIG14,PPROM,RA-A47,SERPINH2,Serpin H1,Arsenic-transactivated protein 3,Collagen-binding protein,Colligin,Rheumatoid arthritis-related antigen,RA-A47,47 kDa heat shock protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
SERPINH1
dry ice
No
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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