Human Serpin H1 (SERPINH1) ELISA Kit

Este producto es parte de SERPINH1 - serpin family H member 1
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Serpin H1 (SERPINH1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx151784
tested applications
ELISA

Description

Human Serpin H1 (SERPINH1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Serpin H1 (SERPINH1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Serpin H1 (SERPINH1)

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Serpin H1 (SERPINH1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
125 pg/ml - 8000 pg/ml
Sensitivity
< 43 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P50454
Gene ID
871
OMIM
600943
Alias
CBP1,CBP2,OI10,gp46,AsTP3,HSP47,PIG14,PPROM,RA-A47,SERPINH2,Serpin H1,Arsenic-transactivated protein 3,Collagen-binding protein,Colligin,Rheumatoid arthritis-related antigen,RA-A47,47 kDa heat shock protein
Background
Elisa Kits for: SERPINH1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

SERPINH1, also known as heat shock protein 47 (HSP47), is a member of the serpin (serine protease inhibitor) superfamily, though it functions differently from classical serpins. Unlike other serpins, SERPINH1 is not a protease inhibitor but rather acts as a molecular chaperone. It plays a crucial role in collagen biosynthesis, aiding the proper folding and stabilization of collagen molecules during their formation. As a collagen-specific chaperone, it is essential in maintaining the structural integrity of connective tissues and contributes significantly to tissue development and repair. The SERPINH1 gene is located on chromosome 11 in humans. Mutations in this gene have been associated with connective tissue disorders, notably osteogenesis imperfecta (OI), a condition characterized by fragile bones.

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