Human Growth Hormone Secretagogue Receptor (GHSR) CLIA Kit
845€ (96 tests)
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name
Human Growth Hormone Secretagogue Receptor (GHSR) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx493740
tested applications
CLIA
Description
Human Growth Hormone Secretagogue Receptor (GHSR) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Growth Hormone Secretagogue Receptor (GHSR) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.055 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | GHSR,growth hormone-releasing peptide receptor,GH-releasing peptide receptor,GHS-R,ghrelin receptor 1a |
| Background | CLIA Kits GHSR |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
GHSR, also known as the ghrelin receptor, is a G protein-coupled receptor that binds the peptide hormone ghrelin, which regulates appetite, energy homeostasis, and growth hormone release. GHSR is widely expressed in the hypothalamus, pituitary gland, and peripheral tissues such as the gastrointestinal tract, where it modulates metabolic and endocrine functions. Activation of GHSR by ghrelin stimulates the release of growth hormone from the pituitary gland and promotes hunger by activating hypothalamic pathways, including the AgRP/NPY neurons. In addition to its role in appetite regulation, GHSR influences glucose metabolism, insulin sensitivity, and cardiovascular function. Dysregulation of GHSR signaling is associated with obesity, type 2 diabetes, and metabolic disorders, where impaired ghrelin signaling contributes to energy imbalance and insulin resistance. In neurobiology, GHSR has neuroprotective effects, enhancing cognitive function and reducing neuroinflammation. GHSR antagonists and agonists are being explored for therapeutic applications in obesity, cachexia, and neurological disorders, positioning it as a critical regulator of metabolism and growth hormone signaling.
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