Human Glycophorin C (GYPC) Protein

Este producto es parte de GYPC - glycophorin C
Human Glycophorin C (GYPC) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein GYPC

proveedor

Abbexa

reference

abx168166

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Glycophorin C Protein is a recombinant Human protein expressed in E. coli.


Background

Glycophorin C (GYPC) is a membrane glycoprotein found primarily on the surface of red blood cells (RBCs). It is a member of the glycophorin family, which includes Glycophorin A (GYPA) and Glycophorin B (GYPB). GYPC plays a crucial role in maintaining the structural integrity of the RBC membrane and contributes to the MNS blood group system. The protein is encoded by the GYPC gene located on chromosome 2. Along with its homologs GYPA and GYPB, GYPC is involved in defining RBC membrane characteristics, including cell shape, flexibility, and interactions with the cytoskeleton. GYPC, specifically, is known to carry the M and N antigens of the MNS blood group system, which are significant in transfusion medicine. In addition to its structural function in the RBC membrane, GYPC plays a role in the function of the erythrocyte by interacting with various signaling molecules and maintaining the membrane's elasticity and resistance to mechanical stresses. Its functional importance in RBCs, as well as its potential relevance in certain disease states, makes it a significant protein in both clinical and biological research.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Glycophorin C (GYPC)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 46.2 kDa Observed MW (SDS-PAGE): 55 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ile128 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

GYPC


dry ice

No


availability

Shipped within 5-7 working days.


alias

Gerbich blood group,GE,GPC,GPD,GYPD,CD236,PAS-2,CD236R,Glycoconnectin,Glycophorin-D,Glycoprotein beta,


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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