Human Glycerol-3-Phosphate Dehydrogenase 1 (GPD1) Protein

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Description
Human GPD1 Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Glycerol-3-Phosphate Dehydrogenase [NAD(+)], Cytoplasmic is produced by our Mammalian expression system and the target gene encoding Met1-Met349 is expressed with a 6His tag at the C-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | GPD1 |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 38.6 kDa Sequence Fragment: Met1-Met349 Tag: C-terminal 6 His tag Validity: The validity for this protein is 6 months. |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM TrisHCl, 10% Glycerol, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at < -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21695 |
| Background | Protein GPD1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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