Human Glutamyl Aminopeptidase (ENPEP) Protein
221€ (10 µg)
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name
Human Glutamyl Aminopeptidase (ENPEP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166697
tested applications
WB, SDS-PAGE
Description
Human Glutamyl Aminopeptidase (ENPEP) Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Glutamyl Aminopeptidase (ENPEP) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 30.7 kDa Observed MW (SDS-PAGE): 30 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu718-Glu948 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q07075 |
| Alias | APA,CD249,gp160,EAP,Aminopeptidase A,AP-A,Differentiation antigen gp160 |
| Background | Protein ENPEP |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Glutamyl aminopeptidase (ENPEP), also known as aminopeptidase A (APA) or CD249, is a zinc-dependent metallopeptidase involved in the regulation of blood pressure, modulation of immune responses, and amino acid metabolism. ENPEP is encoded by the ENPEP gene and functions primarily by cleaving N-terminal glutamyl and aspartyl residues from peptide substrates. As a member of the M1 family of aminopeptidases, ENPEP is a single-pass membrane protein found predominantly in kidney, intestine, and endothelial tissues. It also exists in various immune cells and is a critical regulator in the renin-angiotensin system (RAS), where it facilitates the conversion of angiotensin II to angiotensin III, thereby influencing blood pressure and fluid balance. ENPEP’s role in the RAS system is pivotal because of its impact on hypertension, cardiovascular diseases, and kidney functions. Additionally, ENPEP has implications in immune response regulation, making it a potential target in the treatment of inflammatory and autoimmune diseases. Research into ENPEP function and expression patterns is essential to better understand how this enzyme could be modulated for therapeutic benefits in hypertension, metabolic disorders, and immune system-related diseases.
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