Human Gastric Inhibitory Polypeptide (GIP) Peptide (BSA)

Este producto es parte de GIP - Gastric inhibitory polypeptide ( Receptor)
Human Gastric Inhibitory Polypeptide (GIP) Peptide (BSA)

Pida mas información

935106861

info@markelab.com

Precio

494€ (100 µg)

Protein GIP

proveedor

Abbexa

reference

abx651840

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Gastric Inhibitory Polypeptide (GIP) Protein (BSA) is a protein from Human.


Background

GIP, also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid hormone secreted by K-cells in the duodenum and jejunum in response to nutrient ingestion, particularly glucose, fats, and amino acids GIP acts as a critical incretin hormone that enhances glucose-dependent insulin secretion from pancreatic β-cells by activating cAMP-dependent pathways and protein kinase A signaling GIP also regulates lipid metabolism by stimulating lipoprotein lipase activity in adipose tissue, promoting triglyceride uptake and energy storage GIP further supports bone homeostasis by enhancing osteoblast function, contributing to bone formation and mineralization Dysregulation of GIP levels and signaling is associated with insulin resistance, obesity, and type 2 diabetes where its insulinotropic effects are impaired despite elevated circulating levels GIP-based therapies, including dual GIP/GLP-1 receptor agonists, have shown therapeutic potential in improving glycemic control and promoting weight loss in metabolic disorders

Características del producto

category

Proteins and Peptides


origin

Human


immunogen target

Gastric Inhibitory Polypeptide (GIP)


conjugation

BSA


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

100 µg


size 2

200 µg


size 3

500 µg


size 4

1 mg


size 5

5 mg


observerd MW

Molecular Weight: Calculated MW: 1402.6 Da Concentration: Prior to lyophilization: 200 µg/ml


expression

Synthetic


purity

> 97%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

GIP


dry ice

No


availability

Shipped within 5-15 working days.


alias

Glucose-dependent insulinotropic polypeptide,Incretin


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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