Human Gamma-Glutamylcyclotransferase (GGCT) Protein
234€ (5 µg)
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935106861
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name
Human Gamma-Glutamylcyclotransferase (GGCT) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073189
tested applications
SDS-PAGE
Description
Gamma-Glutamylcyclotransferase is a recombinant enzyme.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Gamma-Glutamylcyclotransferase (GGCT) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 2 weeks. Store at -20 °C for long term storage. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75223 |
| Alias | GGC,GCTG,CRF21,C7orf24,Cytochrome c-releasing factor 21 |
| Background | Protein GGCT |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Gamma Glutamyl Cyclotransferase (GGCT) is an enzyme that plays a crucial role in glutathione metabolism by catalyzing the conversion of gamma-glutamyl peptides to 5-oxoproline and free amino acids. GGCT is involved in maintaining cellular redox balance and regulating glutathione homeostasis, which is essential for cellular protection against oxidative stress and detoxification processes. Dysregulation of GGCT activity has been linked to various pathological conditions, including cancer, where it is often upregulated and contributes to tumor proliferation and chemoresistance. Its role in the gamma-glutamyl cycle also makes it a potential target for therapeutic interventions in oxidative stress-related diseases.
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