Human Gamma-Glutamylcyclotransferase (GGCT) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Gamma-Glutamylcyclotransferase (GGCT) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx387546
tested applications
ELISA
Description
Human Gamma-Glutamylcyclotransferase (GGCT) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GGCT concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Gamma-Glutamylcyclotransferase (GGCT) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O75223 |
| Gene ID | 79017 |
| OMIM | 137170 |
| Alias | GGC,GCTG,CRF21,C7orf24,Cytochrome c-releasing factor 21 |
| Background | Elisa Kits for: GGCT |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Gamma Glutamyl Cyclotransferase (GGCT) is an enzyme that plays a crucial role in glutathione metabolism by catalyzing the conversion of gamma-glutamyl peptides to 5-oxoproline and free amino acids. GGCT is involved in maintaining cellular redox balance and regulating glutathione homeostasis, which is essential for cellular protection against oxidative stress and detoxification processes. Dysregulation of GGCT activity has been linked to various pathological conditions, including cancer, where it is often upregulated and contributes to tumor proliferation and chemoresistance. Its role in the gamma-glutamyl cycle also makes it a potential target for therapeutic interventions in oxidative stress-related diseases.
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