Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Protein

Este producto es parte de B3GAT1 - beta-1,3-glucuronyltransferase 1
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234€ (2 µg)

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935106861
info@markelab.com
name
Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680154
tested applications
SDS-PAGE

Description

Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Protein is a recombinant protein produced in Sf9, Baculovirus cells.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1)
Host
Insect
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
100 µg
Form
Liquid 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
Alias
NK1,CD57,HNK1,LEU7,NK-1,GLCATP,GLCUATP,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,Beta-1,3-glucuronyltransferase 1,Glucuronosyltransferase P,UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase,GlcUAT-P
Background
Protein B3GAT1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Beta-1,3-Glucuronyltransferase 1 (B3GAT1) is an enzyme encoded by the B3GAT1 gene, which plays a critical role in glycosylation processes. It belongs to the family of glycosyltransferases, a group of enzymes responsible for the biosynthesis of glycosaminoglycans (GAGs) and other complex carbohydrates. Specifically, B3GAT1 is involved in the synthesis of the carbohydrate moiety known as the HNK-1 epitope, a unique glycan structure that is found on several proteins in the nervous system and involved in cell-cell and cell-matrix interactions. The enzyme adds a glucuronic acid moiety to the core glycan structure, which is a crucial step in the formation of these specialized carbohydrate chains. B3GAT1 is particularly important in the central nervous system (CNS), where the HNK-1 epitope is associated with neurodevelopmental processes such as cell adhesion, synaptic plasticity, and neuronal migration. The enzyme is also expressed in other tissues, including lymphoid tissues, indicating a broader role in immune regulation and cell signaling.

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