Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Protein

Este producto es parte de B3GAT1 - beta-1,3-glucuronyltransferase 1
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1872€ (1 mg)

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935106861
info@markelab.com
name
Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652658
tested applications
WB, SDS-PAGE

Description

Human Beta-1,3-Glucuronyltransferase 1 (b3GAT1) Protein is a Recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
1 mg
Size 2
5 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 1-2 months.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
NK1,CD57,HNK1,LEU7,NK-1,GLCATP,GLCUATP,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,Beta-1,3-glucuronyltransferase 1,Glucuronosyltransferase P,UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase,GlcUAT-P
Background
Protein B3GAT1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Beta-1,3-Glucuronyltransferase 1 (B3GAT1) is an enzyme encoded by the B3GAT1 gene, which plays a critical role in glycosylation processes. It belongs to the family of glycosyltransferases, a group of enzymes responsible for the biosynthesis of glycosaminoglycans (GAGs) and other complex carbohydrates. Specifically, B3GAT1 is involved in the synthesis of the carbohydrate moiety known as the HNK-1 epitope, a unique glycan structure that is found on several proteins in the nervous system and involved in cell-cell and cell-matrix interactions. The enzyme adds a glucuronic acid moiety to the core glycan structure, which is a crucial step in the formation of these specialized carbohydrate chains. B3GAT1 is particularly important in the central nervous system (CNS), where the HNK-1 epitope is associated with neurodevelopmental processes such as cell adhesion, synaptic plasticity, and neuronal migration. The enzyme is also expressed in other tissues, including lymphoid tissues, indicating a broader role in immune regulation and cell signaling.

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