Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) ELISA Kit

Este producto es parte de B3GAT1 - beta-1,3-glucuronyltransferase 1
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689€ (96 tests)

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935106861
info@markelab.com
name
Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150777
tested applications
ELISA

Description

Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Beta-1,3-Glucuronyltransferase 1 (b3GAT1)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9P2W7
Alias
NK1,CD57,HNK1,LEU7,NK-1,GLCATP,GLCUATP,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,Beta-1,3-glucuronyltransferase 1,Glucuronosyltransferase P,UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase,GlcUAT-P
Background
Elisa kits for B3GAT1
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Beta-1,3-Glucuronyltransferase 1 (B3GAT1) is an enzyme encoded by the B3GAT1 gene, which plays a critical role in glycosylation processes. It belongs to the family of glycosyltransferases, a group of enzymes responsible for the biosynthesis of glycosaminoglycans (GAGs) and other complex carbohydrates. Specifically, B3GAT1 is involved in the synthesis of the carbohydrate moiety known as the HNK-1 epitope, a unique glycan structure that is found on several proteins in the nervous system and involved in cell-cell and cell-matrix interactions. The enzyme adds a glucuronic acid moiety to the core glycan structure, which is a crucial step in the formation of these specialized carbohydrate chains. B3GAT1 is particularly important in the central nervous system (CNS), where the HNK-1 epitope is associated with neurodevelopmental processes such as cell adhesion, synaptic plasticity, and neuronal migration. The enzyme is also expressed in other tissues, including lymphoid tissues, indicating a broader role in immune regulation and cell signaling.

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