Human Alpha-(1,3)-Fucosyltransferase 4 (FUT4) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
662.5€ (96 tests)
Elisa Kits FUT4
proveedor
Abbexareference
abx151600Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Fucosyltransferase 4 / CD15 (FUT4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fucosyltransferase 4 / CD15 (FUT4) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Fucosyltransferase 4 (FUT4)No significant cross-reactivity or interference between Fucosyltransferase 4 (FUT4) and analogues was observed.
Background
FUT4 (fucosyltransferase 4) is a crucial enzyme in the glycosylation process, specifically responsible for catalyzing the transfer of fucose, a hexose sugar, to target glycoproteins and glycolipids. This process is essential in forming fucosylated glycans, such as the Lewis antigens. FUT4 belongs to the broader family of fucosyltransferases, enzymes that facilitate the addition of fucose residues to various substrates. These glycosylation modifications are important for many cellular functions, including cell adhesion, signal transduction, immune response, and development. One of the primary roles of FUT4 is in the synthesis of Lewis X antigen (CD15), a fucosylated oligosaccharide that plays a critical role in mediating cell-cell interactions. FUT4 is encoded by the FUT4 gene, which is located on chromosome 11q21-22 in humans. It is expressed in a variety of tissues but is especially prominent in the bone marrow, placenta, and immune cells. The enzyme's activity has been linked to processes such as leukocyte trafficking, inflammation, and tumor metastasis, due to its ability to regulate the presentation of fucosylated antigens on the cell surface.
Características del producto
category
ELISA Kits
immunogen target
Alpha-(1,3)-Fucosyltransferase 4 (FUT4)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
LeX,CD15,ELFT,FCT3A,FUTIV,SSEA-1,FUC-TIV,Alpha-(1,3)-fucosyltransferase 4,Fucosyltransferase 4,Galactoside 3-L-fucosyltransferase
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FUT4
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
anti- FUT4 antibody
proveedor
FineTestreference
FNab03247Tested Applications
ELISA, IHC, IP, WBreactivity
human,mousestatus
RUOclonality
polyclonalMay catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Precio a consultar
Ver másanti- FUT4 antibody
proveedor
FineTestreference
FNab03248Tested Applications
ELISAreactivity
humanstatus
RUOclonality
polyclonalMay catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Precio a consultar
Ver másAlpha-(1,3)-Fucosyltransferase 4 (FUT4) Antibody
proveedor
Abbexareference
abx011688Tested Applications
ELISA, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
MonoclonalThe product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate st...
362.5€ (100 µl)
Ver más